Anti-proteinuric effect of an endothelin-1 receptor antagonist in puromycin aminonucleoside induced nephrosis in rat.
| Author | |
|---|---|
| Abstract |
:
The pathogenesis of idiopathic nephrotic syndrome (INS) remains unclear although recent studies suggest endothelin 1 (ET-1) and CD80 of podocytes are involved. We investigated the potential of antagonist to ET-1 receptor type A (ETRA) as therapeutic agent through suppression of CD80 in rat model of INS. |
| Year of Publication |
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2018
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| Journal |
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Pediatric research
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| Date Published |
:
2018
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| ISSN Number |
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0031-3998
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| URL |
:
http://dx.doi.org/10.1038/pr.2018.11
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| DOI |
:
10.1038/pr.2018.11
|
| Short Title |
:
Pediatr Res
|
| Download citation |
