Fetal intracranial hemorrhage due to maternal subclinical vitamin K deficiency associated with long-term eating disorder.
| Author | |
|---|---|
| Abstract | 
   :  
              Vitamin K deficiency in pregnant women causes intracranial hemorrhage (ICH) in fetuses. Fetal ICH frequently causes life-threatening and persistent neurological damage. However, indicators for preventing fetal ICH are not established. Two pregnant women developed long-term eating disorders caused by psychosis. They were administered intravenous fluid and vitamin supplementation, excluding vitamin K. The intracranial low-hypoechoic area on fetal ultrasound was suggestive of fetal ICH due to vitamin K deficiency. Their neonates showed severe developmental delay. Laboratory analysis revealed a normal prothrombin time, but elevated protein induced by vitamin K absence II. Pregnant women who have eating disorders more than 3 weeks could develop fetal ICH due to maternal subclinical vitamin K deficiency. Illness duration and protein induced by vitamin K absence II of pregnant woman may be indicators for vitamin K administration to prevent fetal intracranial hemorrhage.  | 
        
| Year of Publication | 
   :  
              2019 
           | 
        
| Journal | 
   :  
              The journal of obstetrics and gynaecology research 
           | 
        
| Volume | 
   :  
              45 
           | 
        
| Issue | 
   :  
              2 
           | 
        
| Number of Pages | 
   :  
              461-465 
           | 
        
| ISSN Number | 
   :  
              1341-8076 
           | 
        
| URL | 
   :  
              https://doi.org/10.1111/jog.13825 
           | 
        
| DOI | 
   :  
              10.1111/jog.13825 
           | 
        
| Short Title | 
   :  
              J Obstet Gynaecol Res 
           | 
        
| Download citation |