<i>TCF7L2</i> Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH).
| Author | |
|---|---|
| Abstract |
:
The rs7903146 T allele in transcription-factor-7-like-2 (TCF7L2) is strongly associated with type 2 diabetes (T2D), but the mechanisms for increased risk remain unclear. We evaluated the physiologic and hormonal effects of TCF7L2 genotype before and after interventions that influence glucose physiology. |
| Year of Publication |
:
2018
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| Journal |
:
Diabetes care
|
| Date Published |
:
2018
|
| ISSN Number |
:
0149-5992
|
| DOI |
:
10.2337/dc17-1386
|
| Short Title |
:
Diabetes Care
|
| Download citation |
