Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib.
| Author | |
|---|---|
| Abstract |
:
Hutchinson-Gilford progeria syndrome (HGPS) is an ultra-rare, fatal, segmental premature aging syndrome caused by the aberrant lamin A protein, progerin. The protein farnesyltransferase inhibitor, lonafarnib, ameliorates some aspects of cardiovascular and bone disease. |
| Year of Publication |
:
2018
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| Journal |
:
Pediatric research
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| Date Published |
:
2018
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| ISSN Number |
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0031-3998
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| URL |
:
http://dx.doi.org/10.1038/pr.2018.9
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| DOI |
:
10.1038/pr.2018.9
|
| Short Title |
:
Pediatr Res
|
| Download citation |
